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ProTx-III

ProTx-III – Ion Channels and Transporters ProTx-III (µ-TRTX-Tp1a; belongs to NaSpTx family 1) has been isolated from the venom of the Peruvian green-velvet tarantula Thrixopelma pruriens at the University of Queensland (Australia). ProTx-III has been described...

ATTO488-ProTx-II

ATTO488-ProTx-II – Ion Channels and Transporters ATTO488-ProTx-II is a fluorescently labeled ProTx-II, a famous Nav1.7 blocker. The wild type ProTx-II blocks Nav1.7  with an IC50 value of around 300 pM, Nav1.2,  Nav1.5 and Nav1.6 with IC50 values of 41 nM, 79 nM...

ProTx-II-Biotin

ProTx-II-Biotin – Ion Channels and Transporters N-ter biotin labeled version of the wild-type ProTx-II (Protoxin-II) which is a toxin that was originally isolated from Thrixopelma pruriens (Peruvian green velvet tarantula).ProTx-II inhibits both...

Cy5-ProTx-II

Cy5-ProTx-II – Ion Channels and Transporters Cy5-ProTx-II is a fluorescently labeled ProTx-II, a famous Nav1.7 blocker. The wild type ProTx-II blocks Nav1.7 with an IC50 value of around 300 pM, Nav1.2, Nav1.5 and Nav1.6 with IC50 values of 41 nM, 79 nM and 26 nM...

8xHis-ProTx-II

8xHis-ProTx-II – Ion Channels and Transporters His-tagged ProTx-II (ProTx-2, Protoxin II) which is a toxin that was originally isolated from Thrixopelma pruriens (Peruvian green velvet tarantula). ProTx-II inhibits both tetrodotoxin-sensitive and...