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Guangxitoxin-1E

Guangxitoxin-1E – Ion Channels and Transporters Guangxitoxin-1E (GxTx-1E) was isolated from the venom of Chilobrachys jingzhao (Chinese earth tiger tarantula). Guangxitoxin-1E was shown to block Kv2.1/KCNB1, Kv2.2/KCNB2 and Kv4.3/KCND3 channels without...

GsMTx4

GsMTx4 – Ion Channels and Transporters GsMTx4 (GsMTx-4, M-theraphotoxin-Gr1a) has been isolated from the venom of the spider Grammostola rosea. This cationic hydrophobic polypeptide blocks selectively the gating of cation selective channels and mechanosensitive...

GsAF-2

GsAF-2 – Ion Channels and Transporters GsAF-II (also termed Kappa-theraphotoxin-Gr2c, GsAF-2) was originally isolated from the venom of Grammostola rosea spider. GsAF-II peptide toxin has antinociceptive and antiarrhythmic effects in mammals. The peptide is...

GsAF-1

GsAF-1 – Ion Channels and Transporters GsAF-1 (also termed β-theraphotoxin-Gr1b, GsAF-I) was originally isolated from the venom of Grammostola rosea spider. GsAF-I peptide toxin is reported to block the following voltage-gated sodium channel isoforms: Nav1.1,...

GrTx1

GrTx1 – Ion Channels and Transporters GrTx1 toxin is a peptide originally isolated from the venom of the spider Grammostola rosea. GrTx1 preferentially blocks voltage-gated sodium channels. GrTx1 toxin is in the same cluster than other famous sodium channel...