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Leiurotoxin-1 Dab7

Leiurotoxin-1 Dab7 – Ion Channels and Transporters Leiuorotoxin-Dab7 (Lei-Dab7) is a mutated version of Leiurotoxin, a peptide identified from the venom of the scorpion Leiurus quinquestriatus hebraeus. The Dab amino acid in position 7 confers to this compound a...

Leiurotoxin-1

Leiurotoxin-1 – Ion Channels and Transporters Scyllatoxin (Leiurotoxin-1) is a neurotoxin that was originally isolated from Leiurus quinquestriatus hebraeus. Scyllatoxin binds and blocks SK channels (small conductance Ca2+-activated K+ channels) in the brain and...

Latartoxin-1a

Latartoxin-1a – Ion Channels and Transporters Latartoxin-1a (U1-zodatoxin-Lt1a, LtTx-1a) has been isolated from the venom of Lachesana tarabaevi spider. It has been described to have insecticidal properties by inducing paralysis and death in some insects.  ...

Kaliotoxin-1

Kaliotoxin-1 – Ion Channels and Transporters Kaliotoxin-1 (KTX1) has been isolated from the venom of the Scorpion Androctonus mauretanicus mauretanicus. Kaliotoxin-1 shows a high structural affinity with Iberiotoxin and Charybdotoxin that inhibit KCa2+ channels...

Jingzhaotoxin-34

Jingzhaotoxin-34 – Ion Channels and Transporters Jingzhaotoxin-34 is a 35-residue polypeptide from the venom of Chinese tarantula Chilobrachys jingzhao. It was initially reported as a potent and selective blocker of the voltage-gated sodium channel NaV1.7 and a...