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NMB-1

NMB-1 – Ion Channels and Transporters NMB-1 (Noxious mechanosensation blocker 1) is an analogue of a peptide isolated from a marine conesnail. This 19 amino acid peptide has shown a 30 fold selectivity in inhibiting slowly adapting mechanically activated...

MT7 – Muscarinic Toxin 7

MT7 – Muscarinic Toxin 7 – Ion Channels and Transporters Muscarinic toxin 7 (MT7 – m1-toxin 1) has been isolated from the venom of the green mamba (Dendroaspis Angusticeps). MT7 potently blocks M1-subtype of muscarinic acetylcholine receptors at a subnanomolar...

Morphiceptin

Morphiceptin – Ion Channels and Transporters Morphiceptin is a four amino acid peptide derived from the ß-casomorphin, a protein fragment itself derived from the digestion of milk protein casein. It is one of the most selective agonist for µ-opoid receptors....

MitTx (MitTx-α + MitTx-β)

MitTx (MitTx-α + MitTx-β) – Ion Channels and Transporters MitTx is a peptide isolated from the Venom of the Texas coral snake Micrurus tener tener. MitTx is a selective agonist for acid-sensing ion channels 1 (ASIC1s) and produces a similar effect than pH drops....

Melittin

Melittin – Ion Channels and Transporters Melittin is a major constituent of the bee venom of Apis mellifera. The N-terminal part of Melittin is hydrophobic and the C-terminal part is hydrophilic. Melittin accumulates in cell membrane which leads to various...