Nociceptin – Neuroscience Peptides

Nociceptin is a potent anti-analgesic, effectively counteracting the effect of pain-relievers. A neuropeptide that modulates nociception, it acts by binding the nociceptin receptor (NOP). Nociceptin does not bind to μ, θ´, or K opioid receptors and thus lacks the addictive potential. Administration of nociceptin leads to sensations of pain and is associated with memory, learning, eating, and anxiety.