Leiurotoxin-1 Dab7 – Ion Channels and Transporters

Leiuorotoxin-Dab7 (Lei-Dab7) is a mutated version of Leiurotoxin, a peptide identified from the venom of the scorpion Leiurus quinquestriatus hebraeus. The Dab amino acid in position 7 confers to this compound a high selectivity for SK2 channels among other channels. Lei-Dab7 exhibits > 200 fold selectivity for SK2 over SK1, SK3, IK, Kv and Kir channels. The IC50 for SK2 is about 3 nM.

Technical specification

	Sequence :	H-AFCNLRZCQLSCRSLGLLGKCIGDKCECVKH (avec Z=Dab)-NH2 (Cys3-Cys21; Cys8-Cys26; Cys12-Cys28)
	MW :	3392.12 g/mol
	Purity :	> 95%
	Counter-Ion :	TFA Salts
	Delivery format :	Lyophilized

Price

Product	Size	Price €	Price $
LED01-0.1 mg	0.1 mg	242 €	194 $
LED01-0.5 mg	0.5 mg	726 €	581 $
LED01-5 x 0.01 mg	5 x 0.01 mg	215 €	172 $
LED01-
LED01-

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