GsAF-1 – Ion Channels and Transporters

GsAF-1 (also termed β-theraphotoxin-Gr1b, GsAF-I) was originally isolated from the venom of Grammostola rosea spider. GsAF-I peptide toxin is reported to block the following voltage-gated sodium channel isoforms: Nav1.1, Nav1.2, Nav1.3, Nav1.4, Nav1.6 and Nav1.7 with respective IC50 values of 0.4, 0.6, 1.3, 0.3, 1.2 and 0.04 µM. In addition, the toxin blocks the hERG1 isoform with an IC50 value of 4.8 µM.

Technical specification

	Sequence :	H-YCQKWLWTCDSERKCCEDMVCRLWCKKRL-NH2 (Cys2-Cys16; Cys9-Cys21; ; Cys15-Cys25)
	MW :	3105.58 g/mol
	Purity :	> 95%
	Counter-Ion :	TFA Salts
	Delivery format :	Lyophilized

Price

Product	Size	Price €	Price $
12GSF001-0.1 mg	0.1 mg	220 €	176 $
12GSF001-0.5 mg	0.5 mg	660 €	528 $
12GSF001-1 mg	1 mg	1 045 €	836 $
12GSF001-
12GSF001-

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