Duck liver-derived peptide 4 – Neuroscience Peptides

Duck liver-derived peptide 4 is a bioactive peptide with high antioxidant activity. The antioxidant activity is attributed to forming hydrogen bonds between their amino acid residues and free radical molecules. Duck liver-derived peptide 4 increases the activities and mRNA expression levels of intracellular antioxidant enzymes (SOD, CAT, and GSH-Px) in HepG2 oxidative damage cell models. Duck liver-derived peptide 4 can reduce the content of malondialdehyde (MDA) and reactive oxygen species (ROS) accumulation, thereby inhibiting intracellular oxidative damage. Duck liver-derived peptide 4 has the following activity: ACE inhibitor, dipeptidyl peptidase IV inhibitor, antioxidant, and antithrombotic. It may be used in the research for food-derived bioactive peptides for modified-food development.