[Cys(AF488)]-Penetratin – Fluorescent Peptides

The Drosophila Antennapedia homeoprotein is able to interact with the phospholipid bilayer to cross into the cell. The 16 residues of penetratin were identified that allowed translocation across the membrane of the cell in to the nucleus. Penatratin has been used as a CPP conjugate in a wide variety of fields particularly to transport hydrophilic molecules. The penetratin domain is present here fused to the green-fluorescent dye Alexa Fluor Dye 488. The tag is suitable for use in imaging and flow cytometry, excitation/ emission at 490/525nm. This fluorescent CPP can be used as a conjugate for intracellular drug delivery or detection of biological structures and thus a key research tool. This peptide is produced to research quality and therefore for research purposes only, and not for use in a therapeutic setting.

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