Cy5-ProTx-II – Ion Channels and Transporters

Cy5-ProTx-II is a fluorescently labeled ProTx-II, a famous Nav1.7 blocker. The wild type ProTx-II blocks Nav1.7 with an IC50 value of around 300 pM, Nav1.2, Nav1.5 and Nav1.6 with IC50 values of 41 nM, 79 nM and 26 nM respectively. The Cy5-ProTx-II version developed by Smartox has potent Nav1.7 blocking activity. It was shown to fully block Nav1.7 at 100 nM concentration

Technical specification

	Sequence :	Cy5-YCQKWMWTCDSERKCCEGMVCRLWCKKKLW-OH (Cys2-Cys16; Cys9-Cys21; Cys15-Cys25)
	MW :	3826.65 g/mol
	Purity :	> 95%
	Counter-Ion :	TFA Salts
	Delivery format :	Lyophilized

Price

Product	Size	Price €	Price $
PTF002-0.01 mg	0.01 mg	121 €	97 $
PTF002-0.1 mg	0.1 mg	616 €	493 $
PTF002-0.5 mg	0.5 mg	1 815 €	1452 $
PTF002-5 x 0.01 mg	5 x 0.01 mg	484 €	388 $
PTF002-

If you’d like to learn more about this toxin, visit our product page on our Smartox website—Our sister company specializing in the synthesis of complex toxins.

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