Acetyl-ccbeta – Amyloid Peptides

The ccβ peptide has been used to study conformational changes in response to stimuli such as temperature and salt. The ccβ peptide adopts a three-stranded alpha-helical coiled-coil structure at low temperature and changes to an amyloid conformation with increasing temperature. The ccβ peptide can be used as a model for prion diseases and in amyloid studies.